Bernardino Ghetti Selected Research

Neurodegenerative Diseases (Neurodegenerative Disease)

12/2023	TAF15 amyloid filaments in frontotemporal lobar degeneration.
11/2023	Distinct Heterocyclic Moieties Govern the Selectivity of Thiophene-Vinylene-Based Ligands Towards Aβ or Tau Pathology in Alzheime's Disease.
4/2023	Thiophene-Based Ligands for Histological Multiplex Spectral Detection of Distinct Protein Aggregates in Alzheimer's Disease.
1/2023	Cross-β helical filaments of Tau and TMEM106B in Gray and White Matter of Multiple System Tauopathy with presenile Dementia.
11/2022	Proteophenes - Amino Acid Functionalized Thiophene-based Fluorescent Ligands for Visualization of Protein Deposits in Tissue Sections with Alzheimer's Disease Pathology.
10/2022	Common Variants Near ZIC1 and ZIC4 in Autopsy-Confirmed Multiple System Atrophy.
10/2022	Structures of α-synuclein filaments from human brains with Lewy pathology.
1/2022	Age-dependent formation of TMEM106B amyloid filaments in human brains.
10/2021	Microglia become hypofunctional and release metalloproteases and tau seeds when phagocytosing live neurons with P301S tau aggregates.
10/2021	Structure-based classification of tauopathies.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Bernardino Ghetti Research Topics

Disease

85	Alzheimer Disease (Alzheimer's Disease) 04/2024 - 06/2002
39	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2023 - 07/2003
25	Frontotemporal Dementia (Semantic Dementia) 10/2023 - 11/2002
22	Dementia (Dementias) 04/2024 - 06/2002
22	Prion Diseases (Transmissible Spongiform Encephalopathies) 11/2023 - 03/2003
17	Tauopathies 05/2024 - 08/2002
17	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 12/2023 - 10/2007
13	Amyloid Plaque 01/2022 - 08/2005
12	Amyloidosis 02/2024 - 03/2003
12	Atrophy 11/2023 - 10/2007
11	Parkinson Disease (Parkinson's Disease) 04/2024 - 09/2005
10	Parkinsonian Disorders (Parkinsonism) 04/2024 - 08/2002
8	Synucleinopathies 04/2024 - 01/2018
8	Sporadic Creutzfeldt-Jakob Disease 04/2024 - 11/2009
8	Cognitive Dysfunction 11/2023 - 08/2012
7	Proteostasis Deficiencies 04/2024 - 03/2007
7	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 02/2024 - 03/2003
7	Multiple System Atrophy 01/2023 - 04/2006
7	Disease Progression 01/2023 - 03/2010
6	Pick Disease of the Brain (Pick's Disease) 05/2024 - 03/2008
6	Corticobasal Degeneration 01/2020 - 10/2007
6	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 01/2020 - 09/2005
5	Chronic Traumatic Encephalopathy 01/2023 - 01/2019
5	Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease) 10/2019 - 11/2008
5	Neuroferritinopathy 01/2016 - 01/2008
5	Scrapie 06/2015 - 09/2005
4	Inflammation (Inflammations) 01/2023 - 07/2012
4	Nervous System Heredodegenerative Disorders 11/2020 - 08/2004
3	Down Syndrome (Down's Syndrome) 03/2024 - 12/2012
3	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 08/2023 - 09/2009
3	TDP-43 Proteinopathies 01/2022 - 12/2014
3	Gliosis 10/2021 - 09/2006
3	Cerebral Cortical Thinning 01/2020 - 11/2013
3	Lewy Body Disease (Lewy Body Dementia) 01/2019 - 09/2005
3	Brain Diseases (Brain Disorder) 09/2011 - 02/2007
2	Sarcoma (Soft Tissue Sarcoma) 12/2023 - 02/2012
2	Death (Near-Death Experience) 11/2016 - 06/2016
2	Ataxia (Dyssynergia) 01/2016 - 07/2003
2	Movement Disorders (Movement Disorder) 01/2016 - 01/2008
2	Iron Overload 01/2016 - 01/2008
2	Hereditary Diffuse Leukoencephalopathy with Spheroids 08/2012 - 12/2011
2	Neuroinflammatory Diseases 01/2011 - 03/2010
1	Liposarcoma 12/2023
1	Sleep Initiation and Maintenance Disorders (Insomnia) 11/2023
1	Fatal Familial Insomnia 11/2023
1	Striatonigral Degeneration 10/2022

Drug/Important Bio-Agent (IBA)

51	Amyloid (Amyloid Fibrils)IBA 03/2024 - 03/2003
36	Proteins (Proteins, Gene)FDA Link 12/2023 - 06/2002
30	Prion ProteinsIBA 11/2023 - 03/2003
19	tau Proteins (tau Protein)IBA 05/2024 - 11/2002
19	Biomarkers (Surrogate Marker)IBA 11/2023 - 08/2012
15	PrionsIBA 04/2024 - 04/2005
12	Peptides (Polypeptides)IBA 01/2023 - 02/2004
11	Protein Isoforms (Isoforms)IBA 05/2024 - 11/2002
11	SynucleinsIBA 04/2024 - 01/2018
11	DNA-Binding Proteins (DNA Binding Protein)IBA 10/2023 - 10/2007
10	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 04/2024 - 01/2006
10	LigandsIBA 03/2024 - 01/2021
9	Presenilin-1IBA 02/2024 - 08/2002
9	Peptide Hydrolases (Proteases)FDA Link 10/2021 - 06/2002
8	ProgranulinsIBA 01/2018 - 09/2006
7	Apolipoproteins E (ApoE)IBA 09/2015 - 10/2007
7	PresenilinsIBA 01/2013 - 06/2002
6	Codon (Codons)IBA 02/2024 - 11/2009
6	IronIBA 11/2020 - 01/2008
6	Amyloid beta-PeptidesIBA 08/2015 - 06/2002
5	ThiophenesIBA 03/2024 - 01/2021
5	2- (4'- (methylamino)phenyl)- 6- hydroxybenzothiazole (Pittsburgh compound B)IBA 01/2022 - 11/2013
4	alpha-SynucleinIBA 10/2022 - 09/2005
4	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 10/2005
4	ApoferritinsIBA 01/2016 - 01/2008
3	Protein AggregatesIBA 04/2023 - 11/2008
3	Valine (L-Valine)FDA Link 10/2021 - 11/2009
3	Methionine (L-Methionine)FDA Link 10/2021 - 11/2009
3	AntibodiesIBA 01/2020 - 02/2007
3	PrPSc ProteinsIBA 01/2017 - 07/2006
3	4- (N- methylamino)- 4'- (2- (2- (2- fluoroethoxy)ethoxy)ethoxy)stilbeneIBA 11/2016 - 08/2015
3	Ferritins (Ferritin)IBA 01/2016 - 01/2008
3	Flavin-Adenine Dinucleotide (FAD)IBA 01/2013 - 11/2008
3	UbiquitinIBA 10/2007 - 08/2002
2	DNA (Deoxyribonucleic Acid)IBA 12/2023 - 02/2012
2	Polysaccharides (Glycans)IBA 11/2023 - 10/2005
2	7- (6- fluoropyridin- 3- yl)- 5H- pyrido(4,3- b)indoleIBA 01/2023 - 10/2018
2	Amyloidogenic ProteinsIBA 01/2021 - 10/2005
2	Nonsense Codon (Nonsense Mutation)IBA 01/2021 - 04/2011
2	Tissue ExtractsIBA 01/2020 - 11/2019
2	Coloring Agents (Dyes)IBA 12/2019 - 11/2018
2	LipidsIBA 09/2019 - 01/2019
2	SilverIBA 01/2019 - 06/2016
2	Phosphotransferases (Kinase)IBA 01/2018 - 12/2014
2	Indicators and Reagents (Reagents)IBA 09/2015 - 09/2006
2	Macrophage Colony-Stimulating FactorIBA 08/2012 - 12/2011
2	NeuroserpinIBA 09/2011 - 06/2002
2	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 03/2008 - 06/2002
2	Levodopa (L Dopa)FDA LinkGeneric 10/2007 - 09/2005
1	ORALIT (ORS)IBA 05/2024
1	Stainless Steel (Steel, Stainless)IBA 04/2024
1	Amino Acids FDA Link 11/2022

Therapy/Procedure

7	Therapeutics 05/2024 - 04/2005
1	Surgical Instruments (Clip) 04/2024